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FORMULATION AND EVALUATION OF BASIL SEEDS OIL BASED WOUND HEALING GEL

  • Unique Paper ID: 166835
  • Volume: 11
  • Issue: 2
  • PageNo: 2401-2411
  • Abstract:
  • The increasing interest in natural and sustainable therapeutic agents has driven research into plant-based formulations for wound care. This study focuses on the development and evaluation of a basil seed oil-based wound healing gel, leveraging the known bioactive properties of basil seed oil without the use of animal models. Basil seed oil, rich in anti-inflammatory, antimicrobial, and antioxidant compounds, was incorporated into a gel matrix using biocompatible polymers such as Carbopol and konjac gum to create a stable and effective topical gel. The formulation process involved optimizing various parameters, including oil concentration, polymer type, and cross-linking agents, to achieve a gel with desirable physicochemical characteristics. Key properties such as pH, viscosity, spreadability, and rheology were meticulously analyzed to ensure the gel’s stability and ease of application. The antimicrobial efficacy of the basil seed oil gel was tested against a spectrum of wound-associated pathogens, including Staphylococcus aureus, Escherichia coli, and Candida albicans, using agar diffusion and minimum inhibitory concentration (MIC) methods. This study underscores the promising potential of basil seed oil in advancing wound care and promoting natural healing processes.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 2
  • PageNo: 2401-2411

FORMULATION AND EVALUATION OF BASIL SEEDS OIL BASED WOUND HEALING GEL

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