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Microwave Assisted Green Catalyzed One-pot Synthesis, Characterization, and Biological Significance of Hexahydroquinolines

  • Unique Paper ID: 167449
  • Volume: 11
  • Issue: 3
  • PageNo: 1103-1108
  • Abstract:
  • A convenient method for the synthesis of hexahydroquinoline through one-pot four component approach using aromatic aldehydes, dimedone, malononitrile and ammonium acetate by using green catalyst under microwave irradiation. Shorter reaction time, high atom economy, easy work up and purification of products are the crucial features of this methodology. These chemicals are easily modifiable to elicit desirable features in the target product by choosing the right precursors. The protocol has been utilized mild reaction conditions, excellent yield, shorter reaction time and simple workup procedure. The synthesized derivatives were obtained in 82-96% yields and were characterized by IR, 1H NMR, 13C NMR, Mass spectra and biological significance.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 3
  • PageNo: 1103-1108

Microwave Assisted Green Catalyzed One-pot Synthesis, Characterization, and Biological Significance of Hexahydroquinolines

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