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Antifungal Activity of Azadirachta Indica and Antigonon Leptopus Leaves Extracts against Candida albicans

  • Unique Paper ID: 168440
  • Volume: 11
  • Issue: 5
  • PageNo: 955-959
  • Abstract:
  • Candidiasis is an opportunistic infection caused by yeast of the genus Candida, primarily Candida albicans, which is the predominant species in fungal infections that can damage the skin and mucosa in humans. Phytoconstituents found in plants has comparable efficacy to synthetic medications in combating harmful microorganisms. The current in-vitro evaluation study was conducted to investigate the antifungal activity of combination of Azadirachta indica and Antigonon leptopus leaves extracts. Antifungal activity of ethanolic extract of leaves of Azadirachta indica and Antigonon leptopus against Candida albicans was carried out utilising agar well diffusion method followed by broth microdilution method using 96 well microtitre plates as per CLSI guidelines. Fluconazole was used a standard in the study. The results showed that the fungal growth was inhibited at the concentrations of 500 µg/mL for the Azadirachta indica extract and 1000 µg/mL for the Antigonon leptopus leaves extracts. Analysis of Azadirachta indica leaves and Antigonon leptopus extracts has been reported for the presence of wide range of phytoconstituents, which are recognised exclusively for their antimicrobial effects. The investigation resulted in a new study on the therapeutic benefits of combination of Azadirachta indica leaves extract with Antigonon leptopus leaves extracts to cure fungal infections. Both leaves extracts have shown improved and broad antifungal properties, making them good choices for treating candidiasis when used in suitable formulations.
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Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 5
  • PageNo: 955-959

Antifungal Activity of Azadirachta Indica and Antigonon Leptopus Leaves Extracts against Candida albicans

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