Toxicology of Datura —Ayurvedic Review

Dr.Devendra M. Bahiram; Dr Neelam S Valhekar; Dr Priyadarshan M Joglekar

Toxicology of Datura —Ayurvedic Review

Authors: Dr.Devendra M. Bahiram, Dr Neelam S Valhekar, Dr Priyadarshan M Joglekar

Unique Paper ID: 169608
Volume: 11
Issue: 6
PageNo: 1303-1306

Keywords: Dhatura stramonium alkaloids atropine cardiac glycosides hyoscamine Ayurveda

Abstract:
Dhatura, a genus of medicinal herb from the Solanaceae family, is credited with toxic as well as medicinal properties. The different plant parts of Dhatura sp., mainly D. stramonium L., commonly known as Dhatura or Jimson Weed, exhibit potent analgesic, antiviral, anti-diarrheal, and anti-inflammatory activities, owing to the wide range of bioactive constituents. With these pharmacological activities, D. stramonium is potentially used to treat numerous human diseases, including ulcers, inflammation, wounds, rheumatism, gout, bruises and swellings, sciatica, fever, toothache, asthma, and bronchitis. The primary phytochemicals investigation on plant extract of Dhatura showed alkaloids, carbohydrates, cardiac glycosides, tannins, flavonoids, amino acids, and phenolic compounds. It also contains toxic tropane alkaloids, including atropine, scopolamine, and hyoscamine. Although some studies on D. stramonium have reported potential pharmacological effects, information about the toxicity remains almost uncertain. Moreover, the frequent abuse of D. stramonium for recreational purposes has led to toxic syndromes. Therefore, it becomes necessary to be aware of the toxic aspects and the potential risks accompanying its use. The present review aims to summarize the phytochemical composition and pharmacological and toxicological aspects of the plant Dhatura.

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Cite This Article

ISSN: 2349-6002
Volume: 11
Issue: 6
PageNo: 1303-1306

Toxicology of Datura —Ayurvedic Review

Available:https://ijirt.org/Article?manuscript=169608

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