“A CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF VRANAROPANI (HEMIGRAPHIS ALTERNATA (Burm.f)) MALAHARA IN THE MANAGEMENT OF SADYOVRANA”

  • Unique Paper ID: 181765
  • Volume: 12
  • Issue: 1
  • PageNo: 5370-5379
  • Abstract:
  • In Ayurvedic classics, Acharya Sushruta has elaborated the varieties of Vrana and its management in eight different chapters. The management of Vrana is evident by the 60 Upakramas (treatment modalities) mentioned by the Acharya. Hemigraphis alternata (Burm.f) T. Anderson (Fam. Acanthaceae) locally known as Murikootti (Malayalam), is a tropical herb used as a folklore medicine for wound healing traditionally. Thus, the study is intended to evaluate the efficacy of Vranaropani Malahara in Sadyovrana by a clinical trial. Methodology:- The outcome of the study is evaluated clinically on a minimum of 60 patients having Sadyovrana divided into two groups A and B. Group A and B patients received Povidone Iodine Ointment and Vranaropani Malahara respectively for application as treatment till the wound healed or a maximum of 15 days. The duration of study was 15 days which included the observations on BT, 1st, 3rd, 5th, 7th, 9th, 11th, 13th and 15th day. Data obtained and statistically analysed. Result:- The result obtained after clinical trials were analyzed statistically and all the observation were subjected to discussions. Overall assessment of the therapy was assessed based on significance of the statistical test value in parameters considered. Conclusion:- Statistically both groups are showing similar effects on Sadyovrana. The treatment with Vranaropani malahara and Povidone Iodine Ointment showed significant changes on some of the clinical features of wound which are subjective and objective parameters. On comparison between 2 groups there is statistically significant difference in all assessment criteria except edema and local rise in temperature. Group-B was more effective than Group-A.

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