Serum C-Reactive Protein as a Prognostic Biomarker in Acute Ischemic Stroke

Dr.Lalith Sagar Reddy Gade; P.Kushal Singh; Dr.Mohd Munaf Ur Razzak; Dr.G.Susmitha

Serum C-Reactive Protein as a Prognostic Biomarker in Acute Ischemic Stroke

Authors: Dr.Lalith Sagar Reddy Gade, P.Kushal Singh, Dr.Mohd Munaf Ur Razzak, Dr.G.Susmitha

Unique Paper ID: 182393
Volume: 12
Issue: 2
PageNo: 1859-1864

Keywords: Acute Ischemic Stroke CRP Barthel Index

Abstract:
Background and Objectives: Stroke is a serious neurological disease which is a major cause of death and disability throughout the world. CRP an inflammatory marker increases in response to stroke, so can be used as a predictor for functional outcome in acute ischemic stroke. In this study, role of serum CRP in assessing the disease severity and short-term functional outcome in an acute ischemic stroke is evaluated. Method: Prospective observational study. Results: Maximum number of cases were between 51-60 years, with a mean age of 62.3 years. Study shows 16% had minor stroke, 58% had moderate stroke, 22% had moderate to severe stroke and 4% had severe stroke. 34 cases got negative and 16 had positive CRP results. CRP and stroke severity by NIHSS score is significantly related in this study (Chi- square value 23.46, p value-0.001). Hypertension (p value 0.047), dyslipidaemia (p value 0.036), smoking (p value 0.031) is positively correlated with the short-term functional outcome after AIS. At the time of discharge 4% cases were independent, 28% with mild, 34% with moderate, 20% with severe and 14% with total dependency. Conclusion: CRP levels in the very early phase of acute ischemic stroke can beused as an independent prognostic factor for short term outcome and for assessing the severity of stroke.

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ISSN: 2349-6002
Volume: 12
Issue: 2
PageNo: 1859-1864

Serum C-Reactive Protein as a Prognostic Biomarker in Acute Ischemic Stroke

Available:https://ijirt.org/Article?manuscript=182393

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