REVIEW ON DIABETES MELLITUS

  • Unique Paper ID: 153243
  • Volume: 8
  • Issue: 6
  • PageNo: 213-218
  • Abstract:
  • Diabetes mellitus may be a cluster of metabolic diseases characterized by hyperglycemia ensuing from defects in hypoglycemic agent secretion, hypoglycemic agent action, or both. The chronic hyperglycemia of diabetes is associated with semi-permanent harm, dysfunction, and failure of varied organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Several unhealthful processes square measure concern with in the development of diabetes. These vary from autoimmune destruction of the beta-cells of the exocrine gland with ensuant insulin deficiency to abnormalities that lead to resistance to insulin action.. In the latter, class a degree of hyperglycemia enough to cause pathologic and purposeful changes in varied target tissues, However while not clinical symptoms, may be present for a long period of time before polygenic disease is recognize. Throughout this asymptomatic period, it is doable to demonstrate an abnormality in macromolecules metabolism by measure of plasma aldohexone in the fasting state or after a challenge with an oral aldohexone load.The degree of hyperglycemia (if any) could amendment over time, looking on the extent of the basic disease process . A illness method could also be gift however might not have progressed far enough to cause hyperglycemia. The same disease process can cause impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) while not fulfilling the standards for the diagnosis of polygenic disease . In some specific with diabetes, adequate glycemic control can be achieved with weight reduction, exercise, and/or oral aldohexone lowering agents. These individuals therefore do not require insulin. Other individuals who have some residual hypoglycemic agent secretion but require exogenous insulin for adequate glycemic control can survive without it. Individuals with extensive beta-cell destruction and therefore no residual insulin secretion need hypoglycemic agent for survival. The seriousness of the metabolic abnormality will progress, regress, or keep an equivalent. Thus, the degree of hyperglycemia reflects the severity of the underlying biological process and its treatment quite the character of the strategy itself.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{153243,
        author = {PRATIBHA R.VANNARWAD and AKSHATA B. LASURE and NANDKISHOR B.BAVAGE and SHYAMLILA B.BAVAGE},
        title = {REVIEW ON DIABETES MELLITUS},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {8},
        number = {6},
        pages = {213-218},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=153243},
        abstract = {Diabetes mellitus may be a cluster of metabolic diseases characterized by hyperglycemia ensuing from defects in hypoglycemic agent  secretion, hypoglycemic agent  action, or both. The chronic hyperglycemia of diabetes is associated  with semi-permanent harm, dysfunction, and failure of varied organs, especially the eyes, kidneys, nerves, heart, and blood vessels.
Several unhealthful processes square measure concern with in the development of diabetes. These vary from autoimmune destruction of the  beta-cells of the exocrine gland with ensuant insulin deficiency to abnormalities that lead to resistance to insulin action.. In the latter, class a degree of hyperglycemia enough to cause pathologic and purposeful changes in varied target tissues, However while not  clinical symptoms, may be present for a long period of time before polygenic disease is recognize. Throughout  this asymptomatic period, it is doable  to demonstrate an abnormality in macromolecules metabolism by measure of plasma aldohexone in the fasting state or after a challenge with an oral aldohexone  load.The degree of hyperglycemia (if any) could amendment  over time, looking  on the extent of the basic disease process . A illness method could also be  gift however might not have progressed far enough to cause hyperglycemia. The same disease process can cause impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) while not  fulfilling the standards  for the diagnosis of polygenic disease . In some specific with diabetes, adequate glycemic control can be achieved with weight reduction, exercise, and/or oral aldohexone  lowering agents. These individuals therefore do not require insulin. Other individuals who have some residual hypoglycemic agent  secretion but require exogenous insulin for adequate glycemic control can survive without it. Individuals with extensive beta-cell destruction and therefore no residual insulin secretion need hypoglycemic agent for survival. The seriousness of the metabolic abnormality will progress, regress, or keep an equivalent. Thus, the degree of hyperglycemia reflects the severity of the underlying biological process and its treatment quite the character of the strategy  itself.},
        keywords = {Diabetes mellitus,type 1diabetes mellitus, type 2 diabetes mellitus, gastational  diabetes mellitus, insulin.},
        month = {},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 8
  • Issue: 6
  • PageNo: 213-218

REVIEW ON DIABETES MELLITUS

Related Articles