Pharmacological and molecular docking study of Imidazole derivatives: A Review

  • Unique Paper ID: 157827
  • Volume: 9
  • Issue: 8
  • PageNo: 167-177
  • Abstract:
  • Molecular docking is frequently employed in contemporary drug design to comprehend drug receptor interaction. In order to anticipate the structure of the intermolecular complex formed between two or more molecules, a process known as molecular docking. This optimization problem describes the "best-fit" orientation of a ligand that binds to a particular protein of interest. In these studies, we learned about the docking analysis of numerous activities, including anticancer, antibacterial, anti-diabetic, anti-inflammatory, anticonvulsant, and antioxidant. The acquired results demonstrate that, for powerful chemicals, tests and docking results are consistent. For executing the molecular design or modification of these imidazole derivatives, as well as for comprehending the action mechanism, these computational studies can provide some relevant references. Considering the well obtained in vitro results, it was thought worthy to perform molecular docking studies, hence screening the compounds, inculcating both in silico and in vitro results.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{157827,
        author = {Mayuri V. Bhosale and Nikhil N. Khot and Mayuri S. Bhadalekar and Abhishek Desai and Dr. N. B. Chougule and Omkar D. Kadam and Saurabh R. patil},
        title = {Pharmacological and molecular docking study of Imidazole derivatives: A Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {9},
        number = {8},
        pages = {167-177},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=157827},
        abstract = {Molecular docking is frequently employed in contemporary drug design to comprehend drug receptor interaction. In order to anticipate the structure of the intermolecular complex formed between two or more molecules, a process known as molecular docking. This optimization problem describes the "best-fit" orientation of a ligand that binds to a particular protein of interest. In these studies, we learned about the docking analysis of numerous activities, including anticancer, antibacterial, anti-diabetic, anti-inflammatory, anticonvulsant, and antioxidant. The acquired results demonstrate that, for powerful chemicals, tests and docking results are consistent. For executing the molecular design or modification of these imidazole derivatives, as well as for comprehending the action mechanism, these computational studies can provide some relevant references. Considering the well obtained in vitro results, it was thought worthy to perform molecular docking studies, hence screening the compounds, inculcating both in silico and in vitro results.},
        keywords = {},
        month = {},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 9
  • Issue: 8
  • PageNo: 167-177

Pharmacological and molecular docking study of Imidazole derivatives: A Review

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