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@article{200275,
        author = {Suraj D. Thakare and Ishan P. Aboti and Rupal A. Kalbhut and Arpita Jena},
        title = {ADVANCES IN TRANSDERMAL DRUG DELIVERY SYSTEMS: FORMULATION APPROACHES, DEVELOPMENT STRATEGIES AND EVALUATION METHODS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2026},
        volume = {12},
        number = {12},
        pages = {344-355},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=200275},
        abstract = {A transdermal drug delivery method involves applying a relatively large dosage of the medication to the inside of a patch that is worn on the skin for a long time. The medication reaches the bloodstream through the skin through a diffusion mechanism. The medicine will continue to diffuse into the blood for a considerable amount of time due to the high concentration on the patch and the low concentration in the blood, keeping the drug's concentration in the blood flow constant. To address the challenges associated with oral medicine administration, the transdermal drug delivery method was developed. Due to hepatic first pass metabolism, the traditional oral dose forms have serious drawbacks, including low bioavailability. For instance, gelatin, zein, cellulose derivatives, etc. In a transdermal patch, backing films are essential because they shield the active layer. Thickness, weight uniformity, drug content, in vitro research, moisture content, and swelling index—basic components of TDDS—can all be used to assess transdermal patches.},
        keywords = {TDDS, Peel adhesion, Shear strength, Reservoir Type, Membrane},
        month = {May},
        }