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@article{165599,
        author = {Ku. Papiha S. Tekade and Dr. Dipti B. Ruikar },
        title = {Research paper of Method Development And Validation of Antidiabetic Drug  in its Pharmaceutical Dosage Form By Suitable Analytical Method  },
        journal = {International Journal of Innovative Research in Technology},
        year = {},
        volume = {11},
        number = {1},
        pages = {1324-1328},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=165599},
        abstract = {The paper describes the invention of a simple, precise, and sensitive approach for detecting saxagliptin in bulk medication and marketed formulations using reverse-phase liquid chromatography. The separation was done on Epic C12 (250 mm×4.6 mm×5 µm) using mobile phase (Methanol: buffer) in the ratio of 80:20 (v/v). The run time was 7 minutes, and the wavelength for saxagliptin was taken as 230 nm. A literature review finds that there are very few HPLC techniques available using this composition of mobile phase. As a result, an attempt was undertaken to create an RP-HPLC technique for saxagliptin.
The devised method was validated in terms of accuracy, precision, linearity, system suitability, LOD and LOQ, robustness, and assay. The linearity ranged from 1-3 μg/ml, with a correlation value of 0.999. The designed and validated RP-HPLC method is used to identify the eluted.
},
        keywords = {Saxagliptin, Antidiabetic, HPLC, Method Development, Validation.},
        month = {},
        }