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@article{169103,
        author = {Shweta Lalit Dhande and Sakshi Daryappa Wani},
        title = {A Review On Current Progress And Perspectives Of Nanoparticles For Chemotherapy},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {6},
        pages = {287-302},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=169103},
        abstract = {Cancer continues to be a major global health challenge, particularly in cases diagnosed at advanced stages with metastases, which are often considered untreatable. Such cases are usually managed to sustain a chronic state of health. The advent of nanotechnology has brought significant advancements to cancer diagnosis and treatment. Nanoparticles, which measure between 1 and 100 nm, present distinct advantages for cancer therapy, including biocompatibility, reduced toxicity, enhanced stability, improved permeability and retention effects, and precise targeting capabilities. They can be classified into various categories, with the nanoparticle drug delivery system designed to leverage the unique characteristics of tumors and their microenvironments. These nanoparticles not only overcome the limitations associated with conventional cancer treatments but also tackle issues related to multidrug resistance. As researchers continue to uncover new mechanisms contributing to this resistance, the interest in nanoparticle applications is steadily increasing. The therapeutic potential of nanoformulations introduces promising new strategies for cancer treatment. This overview will explore the role of nanotechnology in chemotherapy, examining the underlying mechanisms, types of nanoparticles employed, current perspectives, and the significant challenges encountered in the clinical application of these advanced therapies.},
        keywords = {Cancer, Chemotherapy, Nanoparticles, Cellular targeting, drug delivery, Biomaterials.},
        month = {November},
        }