Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{169795,
        author = {Posha Bashir and Mr. Suhail Anjum Rather and Dr Vikas Patel and Dr Amir Bashir and Mr. K S Rana and Dr. Pankaj kaul and Seerath Hamid and Zainab Ali},
        title = {A STUDY OF CLINICO PATHOLOGICAL ANALYSIS OF EPITHELIAL OVARIAN CARCINOMA},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {6},
        pages = {2573-2580},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=169795},
        abstract = {Introduction: Epithelial ovarian carcinoma arises in the cells that line the outer surface of the ovaries and can also develop in the fallopian tube lining. This cancer ranks as the second most prevalent gynecological cancer and is the leading cause of cancer-related deaths among women. Epithelial ovarian carcinomas make up the majority of ovarian cancer cases and are generally linked to a higher risk of spreading to other parts of the body.
This type of cancer constitutes around 95% of all ovarian malignancies, with the remaining 5% comprising nonepithelial types such as germ cell tumors and sex-cord stromal tumors. Epithelial ovarian carcinoma significantly contributes to the morbidity and mortality rates associated with gynecological cancers. While it most commonly affects postmenopausal women, it can occur at any age. Histopathologically, four major subtypes are identified: high-grade serous carcinoma (HGSC), endometrioid carcinoma (EC), clear cell carcinoma (CCC), mucinous carcinoma (MC).
Materials & Methods: This research was conducted between January and October 2024, analysed 98 cases of ovarian carcinoma. We evaluated clinical presentations, as well as gross and microscopic characteristics of the ovarian specimens.
Results: In our study, all participants were female, consistent with the gender-specific nature of epithelial ovarian carcinoma. Of the total cases, 31.63% were diagnosed with epithelial ovarian carcinoma, while 68.37% were negative, indicating a significant number of cases without confirmation of the disease. Among the confirmed cases, serous carcinoma was the most common type (15.31%), followed by endometrioid (7.14%), clear cell (5.10%), and mucinous carcinoma (3.06%). A substantial portion of cases was categorized as negative or not applicable (68.37%). The grades of positive cases ranged from well-differentiated (Grade 1) to poorly differentiated (Grade 4), with Grade 3 being the most frequently observed (12.24%). Additionally, 69.39% of cases were negative for grade classification.
Conclusion: This study demonstrates that epithelial ovarian carcinoma primarily impacts women in their 30s to 50s, with a notable number of cases identified through clinical symptoms and diagnostic methods. This underscores the importance of age and symptom profiles for early detection and diagnosis. While family history may contribute to risk, it is not the only factor, and the diversity of tumor types and grades emphasizes the need for tailored treatment approaches.},
        keywords = {},
        month = {November},
        }