A Critical Review of Piroxicam: From Mechanism to Adverse Effects in Clinical Use

  • Unique Paper ID: 170213
  • PageNo: 3807-3811
  • Abstract:
  • Piroxicam is medications primarily used to treat pain and help relieve symptoms of arthritis (e.g. osteoarthritis, rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. They can be given orally and rectal route. Piroxicam, akin to other nonsteroidal anti-inflammatory drugs (NSAIDs), functions via the inhibition of tissue cyclooxygenases (Cox-1 and -2), resulting in a reduction in the synthesis of pro-inflammatory prostaglandins, which are influential mediators of pain and inflammation. Piroxicam exhibits analgesic properties alongside antipyretic and anti-inflammatory effects. Piroxicam is a monocarboxylic acid amide.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{170213,
        author = {Arzoo Kaushal and Parul verma and Ajeet Pal Singh and Amar Pal Singh},
        title = {A Critical Review of Piroxicam: From Mechanism to Adverse Effects in Clinical Use},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {6},
        pages = {3807-3811},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=170213},
        abstract = {Piroxicam is medications primarily used to treat pain and help relieve symptoms of arthritis (e.g. osteoarthritis, rheumatoid arthritis), such as inflammation, swelling, stiffness, and joint pain. They can be given orally and rectal route. Piroxicam, akin to other nonsteroidal anti-inflammatory drugs (NSAIDs), functions via the inhibition of tissue cyclooxygenases (Cox-1 and -2), resulting in a reduction in the synthesis of pro-inflammatory prostaglandins, which are influential mediators of pain and inflammation. Piroxicam exhibits analgesic properties alongside antipyretic and anti-inflammatory effects. Piroxicam is a monocarboxylic acid amide.},
        keywords = {Piroxicam, NSAIDs, COX-1 & COX-2, Pharmacokinetics, Adverse effects.},
        month = {December},
        }

Cite This Article

Kaushal, A., & verma, P., & Singh, A. P., & Singh, A. P. (2024). A Critical Review of Piroxicam: From Mechanism to Adverse Effects in Clinical Use. International Journal of Innovative Research in Technology (IJIRT), 11(6), 3807–3811.

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