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@article{170434,
        author = {Mr. Rushikesh D. Mohite and Bhaskar A. Mohite and Rushikesh J. Divate and Tushar G. Jadhav},
        title = {Recent Advances in Antiarrhythmic drug therapy : A Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2024},
        volume = {11},
        number = {7},
        pages = {664-670},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=170434},
        abstract = {Current antiarrhythmic drugs (AADs) are generally effective for the acute cardioversion of paroxysmal atrial fibrillation (AF), but their success in maintaining sinus rhythm over the long term is typically moderate. Additionally, the use of AADs is linked to an elevated risk of proarrhythmia, extracardiac side effects, and the worsening of coexisting conditions such as heart failure. Cardiac arrhythmias continue to be a leading cause of death and disability. Despite their moderate efficacy and potential for significant proarrhythmic side effects, antiarrhythmic drugs (AADs) remain a key component of current treatment strategies. However, due to a combination of conceptual, regulatory, and financial challenges, the development of new antiarrhythmic targets and agents has slowed considerably in recent decades. This review explores the critical conceptual factors involved in the development of new antiarrhythmic agents and provides an overview of the novel compounds and formulations that are currently undergoing clinical development.},
        keywords = {Abstract, Introduction, Conceptual Considerations (AAD) Development, Improved derivative of existing drug, Novel AAD formulation, Repurposing of approved drug, Conclusion, References.},
        month = {December},
        }