Anxiolytic Potential of Abies pindrow Royle: A Systematic Review of its Phytochemical Constituents and Anti-Anxiety Activity"

  • Unique Paper ID: 171328
  • PageNo: 3646-3656
  • Abstract:
  • Due to the prevalence of anxiety disorders and their crippling effects, new treatment medicines must be investigated. There have been reports of anxiolytic effects from the herb Abies pindrow Royle, which is utilized in traditional medicine. Though the plant has not been thoroughly studied to support its traditional claims, Abies pindrow Royle (Himalayan Silver Fir; Pinaceae) has been used traditionally to cure anxiety. Investigating the antianxiety properties of different A. pindrow extracts and fractions was therefore planned. Solvents in increasing order of polarity, namely n-hexane, chloroform, methanol, and water, were used to extract the aerial parts of properly identified A. pindrow in a methodical and thorough manner. In mice, all crude extracts were tested for antianxiety effects at dosages of 100, 200, or 400 mg/kg, p.o. A. pindrow's effectiveness was statistically contrasted with that of the common anxiolytic medication. When compared to the control, the chloroform and methanol extracts showed the most antianxiety effects and were statistically equivalent to the usual medication at doses of 200 and 400 mg/kg, respectively. n-hexane, ethyl acetate, and 1-butanol were the solvents used to partition the bioactive methanol extract in ascending order of polarity. Additionally, mice were given dosages of 25 or 50 mg/kg, p.o., of all fractions to test their antianxiety properties. At a dose of 50 mg/kg, only the ethyl acetate fraction (EAF) demonstrated considerable antianxiety effect comparable to the conventional medication.Current research has scientifically confirmed A. pindrow's traditional claims of antianxiety properties. It has been proposed that flavonoids from the aerial sections of A. pindrow may help cure anxiety problems.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{171328,
        author = {Shagun and Priyanka Thakur and Shivani Dixit and Amisha kumari and priyanshu},
        title = {Anxiolytic Potential of Abies pindrow Royle: A Systematic Review of its Phytochemical Constituents and Anti-Anxiety Activity"},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {7},
        pages = {3646-3656},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=171328},
        abstract = {Due to the prevalence of anxiety disorders and their crippling effects, new treatment medicines must be investigated. There have been reports of anxiolytic effects from the herb Abies pindrow Royle, which is utilized in traditional medicine. Though the plant has not been thoroughly studied to support its traditional claims, Abies pindrow Royle (Himalayan Silver Fir; Pinaceae) has been used traditionally to cure anxiety. Investigating the antianxiety properties of different A. pindrow extracts and fractions was therefore planned. Solvents in increasing order of polarity, namely n-hexane, chloroform, methanol, and water, were used to extract the aerial parts of properly identified A. pindrow in a methodical and thorough manner. In mice, all crude extracts were tested for antianxiety effects at dosages of 100, 200, or 400 mg/kg, p.o. 
 A. pindrow's effectiveness was statistically contrasted with that of the common anxiolytic medication. When compared to the control, the chloroform and methanol extracts showed the most antianxiety effects and were statistically equivalent to the usual medication at doses of 200 and 400 mg/kg, respectively. n-hexane, ethyl acetate, and 1-butanol were the solvents used to partition the bioactive methanol extract in ascending order of polarity. Additionally, mice were given dosages of 25 or 50 mg/kg, p.o., of all fractions to test their antianxiety properties. At a dose of 50 mg/kg, only the ethyl acetate fraction (EAF) demonstrated considerable antianxiety effect comparable to the conventional medication.Current research has scientifically confirmed A. pindrow's traditional claims of antianxiety properties. It has been proposed that flavonoids from the aerial sections of A. pindrow may help cure anxiety problems.},
        keywords = {Pindrow, Abies Royle, phytochemical components, anti-anxiety action, systematic review.},
        month = {January},
        }

Cite This Article

Shagun, , & Thakur, P., & Dixit, S., & kumari, A., & priyanshu, (2025). Anxiolytic Potential of Abies pindrow Royle: A Systematic Review of its Phytochemical Constituents and Anti-Anxiety Activity". International Journal of Innovative Research in Technology (IJIRT), 11(7), 3646–3656.

Related Articles