Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{172454,
        author = {Rallabandi Lakshmi Pavani and Pinninti Venkata sai and Narala Balaji},
        title = {A Comprehensivereview of vincristine – A Vinca alkaloid used for treatment of chemotherapy and its importance},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {8},
        pages = {3226-3229},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172454},
        abstract = {Vincristine is a chemotherapeutic agent obtained from natural alkaloid plant source Catharanthus roseus. Vincristine has been significantly useful in treatments of lung cancer.lymphocyte based leukaemia, glioblastomas and acute myeloid leukaemia, glioblastomas and acute myeloid leukaemia.Vincristine possesses low cancer tissue affinity and at higher dose often led to irreversible neurotoxicity. vincristine attaches the tubulin fibrils and prevents filaments polymerization that permanently led to mitotis inhibition in cancer cells.In this review ,we have summarized the chemotherapeutic role of vincristine and it’s mechanism of action , importance in cancer prevention associated with vincristine delivery .Moreover , application of vincristine and effect on anticancer efficacy are also being discussed.},
        keywords = {Vincristine, chemotherapy, alkaloids, cancer.},
        month = {January},
        }