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@article{172536,
        author = {P.Sowmya and P.Ruchitha and P.Ashwini and P.Varshini and P.Satish and Dr. S. Sridhar},
        title = {NEXT GENERATION ANTIBIOTICS FOR COMBATING ANTIMICROBIAL RESISTANCE},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {9},
        pages = {325-336},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172536},
        abstract = {A major global health concern, antimicrobial resistance (AMR) is caused by the overuse and abuse of antibiotics in numerous fields, which results in the growth of resistant microorganisms. This serious public health concern jeopardizes our capacity to treat common infections. Current antibiotics are ineffective against many diseases due to antimicrobial resistance, which is a serious danger to world health. It is especially common in underdeveloped nations where infectious diseases are still prominent, antibiotic usage is widespread in both humans and animals, and switching from older to newer antibiotics is difficult because of their high cost. The pressing demand for new antibiotics has not been met by conventional bioactivity-guided natural product discovery, mostly because of high rediscovery rates and scarce resources. By the year 2050, antimicrobial resistance (AMR) is expected to cause 10 million deaths annually worldwide, making it a chronic public health concern. AMR happens when bacteria, fungi, viruses, and parasites do not react to antimicrobial treatments in both humans and animals, allowing the microorganism to survive inside the host. The overuse and misuse of antibiotics, especially their improper use, is still the key factor causing the current crisis and adding to the worldwide burden of antimicrobial resistance. The developments in next-generation antibiotics, their modes of action, and their potential to fight AMR are highlighted in this research. Developmental problems and new therapeutic approaches are also covered.},
        keywords = {Antibiotic, Anti-microbial Resistance, Drug, Enzymes, Treatment, WHO.},
        month = {January},
        }