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@article{172794,
        author = {Santhi Sree .Vemulapalli and Muralidhar Rao.Akkaladevi},
        title = {FORMULATION, DEVELOPMENT AND EVALUTION OF TELMISARTAN        IMMEDIATE RELEASE OF TABLET},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {9},
        pages = {1260-1268},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=172794},
        abstract = {The primary aim of this study was to develop and evaluate Telmisartan immediate-release tablets for effective hypertension management. Telmisartan, an angiotensin II receptor blocker, is commonly prescribed for hypertension, but its formulation into an immediate-release tablet requires optimization to ensure optimal bioavailability and therapeutic efficacy. Telmisartan immediate release tablets were formulated using various excipients and processing techniques. The formulation process included blending Telmisartan with different fillers, binders, and disintegrants to achieve the desired tablet characteristics. The tablets were then subjected to a range of evaluations including physical characteristics (hardness, friability, and weight variation), in vitro dissolution studies, testing. The dissolution profiles were compared with a commercially available reference product to assess the bioequivalence. The developed tablets demonstrated satisfactory physical properties, with appropriate hardness, low friability, and consistent weight variation. In vitro dissolution studies showed that the formulated tablets had a dissolution profile comparable to that of the reference product, meeting the required pharmacopoeial standards. The study successfully developed Telmisartan immediate-release tablets with desirable physical characteristics and a dissolution profile that supports their efficacy in managing hypertension. The formulation meets the required standards for pharmaceutical quality and has potential for clinical use, offering available alternative to existing products. Telmisartan, immediate release tablets, formulation development, in vitro dissolution, pharmaceutical evaluation.},
        keywords = {Telmisartan, immediate-release tablets, formulation development, in vitro dissolution, pharmaceutical evaluation.},
        month = {February},
        }