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@article{173384,
        author = {Naina Sara Sabu and Anjana Deepthi V. and Aparna Subhash and Ardra Prathapan and Harisankar K.S and Anwar Basheer},
        title = {IN–VITRO ANTIHISTAMINIC EFFICACY OF ETHANOLIC EXTRACT OF PHYLLANTHUS AMARUS SCHUMACH. AND THONN. - A RESEARCH ARTICLE},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {10},
        pages = {213-219},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=173384},
        abstract = {Current treatments for allergic-mediated conditions are often linked to a range of side effects. The traditional use of plant extracts in healthcare offers a promising potential for discovering new pharmaceutical compounds. The aim of the present study was to assess the anti-histaminic efficacy of Phyllanthus amarus Schumach. and Thonn. using the ethanolic extract of its fresh leaves and stem. The experiment was conducted in smooth muscles of isolated chicken ileum as it is rich in histamine receptors. The pharmacological effects observed in the experimental in-vitro model are believed to be attributed to the alkaloids, flavonoids, tannins, lignans and other chemical components present in the plant extract. These results indicate that the ethanolic extract of the fresh leaves and stems of P. Amarus demonstrates notable anti-histaminic effects.},
        keywords = {Phyllanthus amarus Schumach. And Thonn., Antihistaminic efficacy, Chlorpheniramine maleate, Histamine, DRC},
        month = {March},
        }