Review: Terpenes importance in Nano vesicular drug delivery system

  • Unique Paper ID: 173390
  • PageNo: 596-603
  • Abstract:
  • Terpenes are a group of phytocompounds that have been used in medicine for periods due to their significant role in human health. So far, they have been examined for healing purposes as antibacterial, anti-inflammatory, antitumoral agents, and the clinical potential of this class of compounds has been increasing continuously as a source of pharmacologically interesting agents also in relation to topical administration. Major difficulties in achieving sustained delivery of terpenes to the skin are connected with their low solubility and stability as well as poor cell penetration. In order to overcome these disadvantages new delivery technologies based on nanostructures are proposed to improve bioavailability and allow controlled release. This review highlights the potential properties of terpenes loaded in several types of lipid-based nanocarriers (liposomes, solid lipid nanoparticles, and nanostructured lipid carriers) used to overcome free terpenes form limitations and potentiate their therapeutic properties for topical administration. In this article, different categories of terpenes that are used as penetration enhancers in pharmaceutical products their mechanism to improve the penetration and terpenes application in transdermal route were discussed along with the pharmaceutical application of invasomes in the transdermal drug delivery.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{173390,
        author = {K.SHOBANA and Dr.M.RAJESH and S.MUHAMED SATHAM USSAIN and SIVAPRAKASH K and SUBRAMANIAN.L and SINGARANI.S and YAMINI P and SURYA VIJAY . P},
        title = {Review: Terpenes importance in Nano vesicular drug delivery system},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {10},
        pages = {596-603},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=173390},
        abstract = {Terpenes are a group of phytocompounds that have been used in medicine for periods due to their significant role in human health. So far, they have been examined for healing purposes as antibacterial, anti-inflammatory, antitumoral agents, and the clinical potential of this class of compounds has been increasing continuously as a source of pharmacologically interesting agents also in relation to topical administration. Major difficulties in achieving sustained delivery of terpenes to the skin are connected with their low solubility and stability as well as poor cell penetration. In order to overcome these disadvantages new delivery technologies based on nanostructures are proposed to improve bioavailability and allow controlled release. This review highlights the potential properties of terpenes loaded in several types of lipid-based nanocarriers (liposomes, solid lipid nanoparticles, and nanostructured lipid carriers) used to overcome free terpenes form limitations and potentiate their therapeutic properties for topical administration. In this article, different categories of terpenes that are used as penetration enhancers in pharmaceutical products their mechanism to improve the penetration and terpenes application in transdermal route were discussed along with the pharmaceutical application of invasomes in the transdermal drug delivery.},
        keywords = {Effect, Invasomes, Synergism, Terpenes.},
        month = {March},
        }

Cite This Article

K.SHOBANA, , & Dr.M.RAJESH, , & USSAIN, S. S., & K, S., & SUBRAMANIAN.L, , & SINGARANI.S, , & P, Y., & P, S. V. .. (2025). Review: Terpenes importance in Nano vesicular drug delivery system. International Journal of Innovative Research in Technology (IJIRT), 11(10), 596–603.

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