Formulation and Evaluation of a Novel Wound Healing Cream Incorporating Lupeol and Centella Asiatica Extracts

  • Unique Paper ID: 174016
  • Volume: 11
  • Issue: 10
  • PageNo: 2406-2410
  • Abstract:
  • Wound management is a crucial component of clinical care, particularly for chronic wounds that greatly affect the quality of life. This study focuses on the formulation and assessment of an herbal wound healing cream that harnesses the synergistic effects of two bioactive compounds—lupeol and Centella asiatica extract. Lupeol, a pentacyclic triterpenoid derived from Crataeva nurvala, possesses strong anti-inflammatory, antimicrobial, and antioxidant properties. Centella asiatica, a renowned medicinal herb, enhances wound healing by stimulating collagen production and tissue regeneration. The cream was formulated using a conventional oil-in-water emulsion method and evaluated based on key physical characteristics, including appearance, pH, viscosity, spreadability, and specific gravity, alongside safety and efficacy parameters. The findings revealed a smooth, uniform, and non-irritating cream with excellent spreadability and a skin-compatible pH. This research underscores the value of integrating traditional herbal medicine with modern formulation techniques to develop effective wound care solutions.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{174016,
        author = {Mr.Mujeeb Muhamadhusen Shaikh and Alisha Anwar shaikh},
        title = {Formulation and Evaluation of a Novel Wound Healing Cream Incorporating Lupeol and Centella Asiatica Extracts},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {10},
        pages = {2406-2410},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=174016},
        abstract = {Wound management is a crucial component of clinical care, particularly for chronic wounds that greatly affect the quality of life. This study focuses on the formulation and assessment of an herbal wound healing cream that harnesses the synergistic effects of two bioactive compounds—lupeol and Centella asiatica extract. Lupeol, a pentacyclic triterpenoid derived from Crataeva nurvala, possesses strong anti-inflammatory, antimicrobial, and antioxidant properties. Centella asiatica, a renowned medicinal herb, enhances wound healing by stimulating collagen production and tissue regeneration. The cream was formulated using a conventional oil-in-water emulsion method and evaluated based on key physical characteristics, including appearance, pH, viscosity, spreadability, and specific gravity, alongside safety and efficacy parameters. The findings revealed a smooth, uniform, and non-irritating cream with excellent spreadability and a skin-compatible pH. This research underscores the value of integrating traditional herbal medicine with modern formulation techniques to develop effective wound care solutions.},
        keywords = {Wound healing, Lupeol, Centella Asiatica, Herbal cream, Skin regeneration},
        month = {March},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 10
  • PageNo: 2406-2410

Formulation and Evaluation of a Novel Wound Healing Cream Incorporating Lupeol and Centella Asiatica Extracts

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