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@article{174727,
author = {Dr Amruta Patil and Dr V V Hattiholi and Dr Santosh D Patil},
title = {Pituitary stalk interruption syndrome},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {11},
number = {11},
pages = {427-429},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=174727},
abstract = {Pituitary Stalk Interruption Syndrome (PSIS) is a rare congenital disorder characterized by an absent or hypoplastic pituitary stalk, often leading to multiple endocrinological abnormalities. It typically presents in early childhood with growth hormone deficiency, hypothyroidism, hyperprolactinemia, and adrenal insufficiency, resulting in short stature, delayed puberty, hypoglycemia, and developmental delays. Birth complications such as breech presentation and neonatal jaundice are common. MRI plays a crucial role in diagnosis, revealing structural abnormalities, including an absent or ectopic pituitary gland, hypothalamic displacement, and third ventricle enlargement. Early diagnosis and hormonal therapy are essential for managing symptoms and preventing long-term complications.},
keywords = {Pituitary stalk interruption syndrome (PSIS), panhypopituitarism, Ectopic Posterior Pituitary, hypoplastic pituitary stalk},
month = {March},
}
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