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@article{175845,
author = {Samreena zafer and Artiz Ashiq and Ms Rizwana Ashiq},
title = {The effect of Anaesthesia on Postoperative cognitive dysfunction (POCD) -----(this review aims to highlight the impacts of anaesthesia in developing POCD)},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {11},
number = {11},
pages = {4327-4329},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=175845},
abstract = {Postoperative cognitive dysfunction (POCD) is a common complication of surgery, affecting up to 30% of patients after major procedures. POCD is characterized by a decline in cognitive functions such as memory, attention, and executive function, significantly affecting patients’ quality of life and functional independence. Anaesthesia, a critical component of surgical care, has complex effects on cognitive function. While it ensures pain relief and patient comfort during surgery, it may negatively impact cognition, particularly in older adults. Short-term changes in cognitive performance during the first few days to weeks after surgery are well documented. However, POCD is not formally recognized in the DSM-5-TR. Some studies report a 36% incidence of cognitive decline at 6 weeks and 42% at 5 years post-coronary artery bypass grafting (CABG). The incidence after non-cardiac surgery in patients over 65 is about 26% at 1 week and 10% at 3 months. Multiple factors contribute to POCD, including patient-related variables (e.g., age, education level, comorbidities), surgical variables (e.g., type and duration), and anaesthesia-related factors (e.g., type and dosage of anaesthetics). Research suggests certain anaesthetic agents and techniques, particularly general anaesthesia and agents like benzodiazepines and anticholinergics, may be associated with a higher risk of POCD.},
keywords = {POCD (Postoperative cognitive dysfunction) ,GA (general anaesthesia) ,SG (surgical variables) ,Coronary artery bypass grafting (CABG).},
month = {April},
}
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