Fever With Lymphadenopathy: A Rare Case Of Kikuchi-Fujimoto Disease

  • Unique Paper ID: 176353
  • Volume: 11
  • Issue: 11
  • PageNo: 6390-6392
  • Abstract:
  • Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare, benign, and self-limiting condition typically affecting young women. Its clinical presentation often mimics other infectious, autoimmune, or malignant causes of lymphadenopathy such as tuberculosis, systemic lupus erythematosus (SLE), or lymphoma, thereby complicating timely diagnosis. We report a unique case of KFD in a 32-year-old female who presented with fever, lymphadenopathy, and autoimmune features consistent with an overlap syndrome involving SLE and Scleroderma, suggestive of Mixed Connective Tissue Disease (MCTD). Histopathological examination of lymph nodes revealed characteristic features of KFD. The case highlights the need for a high index of clinical suspicion, thorough differential diagnosis, and the critical role of lymph node biopsy to avoid misdiagnosis and unnecessary treatments.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{176353,
        author = {Dr Nakka Venkata Ramanadh and Dr. E. Sireesha and Dr. K. Siva Prasad and Dr . Ram Siva Nayak},
        title = {Fever With Lymphadenopathy: A Rare Case Of Kikuchi-Fujimoto Disease},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {11},
        pages = {6390-6392},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=176353},
        abstract = {Kikuchi-Fujimoto Disease (KFD), also known as histiocytic necrotizing lymphadenitis, is a rare, benign, and self-limiting condition typically affecting young women. Its clinical presentation often mimics other infectious, autoimmune, or malignant causes of lymphadenopathy such as tuberculosis, systemic lupus erythematosus (SLE), or lymphoma, thereby complicating timely diagnosis. We report a unique case of KFD in a 32-year-old female who presented with fever, lymphadenopathy, and autoimmune features consistent with an overlap syndrome involving SLE and Scleroderma, suggestive of Mixed Connective Tissue Disease (MCTD). Histopathological examination of lymph nodes revealed characteristic features of KFD. The case highlights the need for a high index of clinical suspicion, thorough differential diagnosis, and the critical role of lymph node biopsy to avoid misdiagnosis and unnecessary treatments.},
        keywords = {},
        month = {April},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 11
  • Issue: 11
  • PageNo: 6390-6392

Fever With Lymphadenopathy: A Rare Case Of Kikuchi-Fujimoto Disease

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