Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

@article{176589,
        author = {Mr Shaikh Mohammed Umair Rehan and Mr Naseem Qureshi and Miss Bushra hundekari},
        title = {The Role of Myrica Nagi Bark in Tumor Suppression and Bowel Regulation: A Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {11},
        pages = {6734-6740},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=176589},
        abstract = {Myrica nagi, commonly known as bayberry, is a medicinal plant extensively used in traditional and folk medicine systems across Asia. Among the various parts of the plant, the bark has attracted increasing scientific attention due to its broad spectrum of pharmacological activities. Rich in bioactive compounds such as flavonoids, tannins, saponins, and phenolic acids, the bark of Myrica nagi demonstrates potent antioxidant, anti-inflammatory, antimicrobial, and anticancer properties. These constituents not only help combat oxidative stress but also modulate inflammatory pathways and inhibit microbial growth, thereby contributing to overall health.
Recent preclinical studies suggest that Myrica nagi bark may have significant therapeutic potential in the prevention and management of cancer, particularly colorectal cancer. The antitumor effects are believed to stem from its ability to regulate cell proliferation, induce apoptosis in cancer cells, and inhibit angiogenesis and metastasis. Furthermore, the bark’s role in promoting gastrointestinal health has been highlighted in various studies, where it has shown promising results in alleviating symptoms of irritable bowel syndrome (IBS) and other digestive disorders. Its potential to restore gut microbial balance and enhance bowel motility makes it a valuable candidate for further research in gastrointestinal therapeutics.
This review critically examines the phytochemical composition of Myrica nagi bark and its diverse pharmacological activities, with a specific focus on its implications for cancer prevention and gastrointestinal regulation. By consolidating current findings, the article aims to provide a comprehensive overview of how Myrica nagi bark may serve as a natural, plant-based intervention for tumor inhibition and bowel health improvement. The evidence presented here could pave the way for future clinical applications and drug development initiatives centered around this traditionally used yet scientifically underexplored botanical resource.},
        keywords = {Myrica Nagi, tumor suppression, bowel regulation, bioactive compounds, flavonoids, tannins, alkaloids, cancer prevention, anti-inflammatory, antioxidant, medicinal plants, phytochemistry.},
        month = {April},
        }