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@article{176851, author = {Asha D and Sowmya B and Geetha M M}, title = {ROLE OF DIFFERENT MATERIALS EMPLOYED FOR NATURAL TISSUE REPLACEMENT}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {8}, number = {10}, pages = {707-712}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=176851}, abstract = {Different materials are employed for natural tissue replacement based on their properties, biocompatibility, and specific roles in mimicking or supporting the function of natural tissues. Each material plays a specific role in tissue engineering, selected based on the target tissue's requirements, such as mechanical strength, degradation rate, and biological activity. Natural tissue replacement leverages a spectrum of biomaterials—ranging from biologically derived polymers to synthetic polymers, ceramics, metals, composites, hydrogels, and decellularized extracellular matrices—each selected for properties such as biocompatibility, degradability, mechanical strength, and bioactivity. Natural polymers mimic the native extracellular matrix to support cell adhesion and signaling; synthetic polymers allow precise tuning of degradation and mechanics; ceramics and bioactive glasses promote bone ingrowth; metals and alloys provide load-bearing durability; composites synergize multiple properties; hydrogels recreate soft-tissue environments and enable drug/cell delivery; and decellularized matrices retain native architecture and biological cues to guide regeneration. This work explains the different materials employed in it.}, keywords = {Natural Tissue, Replacement, Biocompatibility, Biological Activity}, month = {April}, }
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