killer yeasts: Mechanisms, Applications in Medicine and Biocontrol, and Future Prospects

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Saidunnisa Begum Mohammad; Gude. Sri Sai Satyanarayana; Harika Pathuri; Dr.Poosarla Chandrashekar; Dr.Vatsalya kommalpati; Dr.Kiran Kumar Katappagari

killer yeasts: Mechanisms, Applications in Medicine and Biocontrol, and Future Prospects

Authors: Saidunnisa Begum Mohammad, Gude. Sri Sai Satyanarayana, Harika Pathuri, Dr.Poosarla Chandrashekar, Dr.Vatsalya kommalpati, Dr.Kiran Kumar Katappagari

Unique Paper ID: 177143
Volume: 11
Issue: 12
PageNo: 3675-3678

Keywords: Killer toxins Saccharomyces cerevisiae protein secretion yeast virology antimicrobial properties.

Abstract:
The discovery of the yeast killer system, particularly in Saccharomyces cerevisiae, has significantly advanced various areas of biology. Researchers have gained insights into fundamental processes like protein processing and secretion, shedding light on how proteins are synthesized and transported within cells. Studies of killer toxins, similar to secreted proteins, have revealed mechanisms involved in post-translational modifications and secretion, providing a deeper understanding of eukaryotic cell biology. Additionally, the mode of action of killer toxins, which target specific receptors, has facilitated the study of yeast and fungal cell wall structures, helping to develop strategies for combating infections caused by pathogens like Candida albicans and Sporothrix schenckii. Over the past three decades, research on killer yeasts has also advanced our knowledge of virus-host interactions and yeast virology. Researchers like Schmitt & Breinig have explored killer strains' effects on related species, providing insights into ecological and industrial applications. Furthermore, Pieczynska et al. found that around 10% of strains carry killer viruses, while 25% resist viral toxins. While killer yeasts are valued for their antimicrobial properties, they pose challenges in large-scale fermentation processes, where they can inhibit starter cultures and disrupt production. Nonetheless, their potential in biomedicine and gene technology remains an active research area.

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Cite This Article

ISSN: 2349-6002
Volume: 11
Issue: 12
PageNo: 3675-3678

killer yeasts: Mechanisms, Applications in Medicine and Biocontrol, and Future Prospects

Available:https://ijirt.org/article?manuscript=177143

Impact Factor
8.01 (Year 2024)

UGC Approved
Journal no 47859

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