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@article{177750,
        author = {Aditya B. Changan and Pranali P.Bagal and Mayuri Y. Bansode and Saurabh S. Bagal and Rohan C. Baad and Dipali S. Mane and Dr.Amit N. Panaskar and Dr.Bhagyashri A.Panaskar},
        title = {Formulation and evaluation of safflower oil and calcium hydroxide ointment for healing burn skin},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {12},
        pages = {2950-2957},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=177750},
        abstract = {Burn injuries represent a global public health challenge, often resulting from accidents or disasters, and in some cases, indicating child abuse. Large burns can lead to systemic complications such as burn shock and require comprehensive treatment strategies including inflammation management, infection control, nutritional support, fluid resuscitation, and wound coverage. Modern therapies involve advanced techniques like stem cells and engineered skin substitutes but are often expensive and inaccessible in developing regions. Traditional Iranian Medicine (TIM) offers affordable, time-tested alternatives, such as Lime Salve (L.S.), composed of calcium hydroxide (lime water), sesame oil, and beeswax. Calcium hydroxide promotes tissue healing through mineralization, antimicrobial action, and regulation of wound healing phases including hemostasis, inflammation, proliferation, and remodeling. Safflower oil, rich in linoleic acid and antioxidants, provides anti-inflammatory, antimicrobial, and anti-aging benefits while promoting collagen synthesis and angiogenesis.A novel herbal ointment was formulated using lime water, safflower oil, methyl paraben (as preservative), and rose oil via an emulsifying ointment method. The formulation was evaluated for physical parameters including pH, colour, odour, spread ability, solubility, washability, and skin irritation. Results confirmed good spreadability, solubility, ease of washing, and non-irritant properties, suggesting this traditional formulation as a promising, accessible alternative for burn wound management.},
        keywords = {},
        month = {May},
        }