A study of the clinicohaematological profile of the patients presenting with thrombocytopenia in tertiary care hospital.

  • Unique Paper ID: 177804
  • Volume: 11
  • Issue: 12
  • PageNo: 3016-3022
  • Abstract:
  • Background: Thrombocytopenia is a common finding in patients admitted in tertiary care centre and its etiology is diverse. Aim: To study the clinicohaematological profile of the patients presenting with thrombocytopenia in tertiary care hospital. Materials and Methods: This study was a prospective study conducted over the period of two years conducted at MGM Medical College Aurangabad.With the relevant clinical and investigatory findings all patients with a platelet count of less than 1,50,000 were included in the study. Result: The study included 80 patients, with the majority being males (62.50%) and a significant proportion aged between 18-30 years (40.00%).Platelet count analysis showed that 45.00% of the patients had counts below 50,000 per cubic millimeter, indicating severe thrombocytopenia.Etiological analysis revealed that febrile illnesses, particularly dengue fever (53.75%), were the most common cause of thrombocytopenia, followed by haematological disorders (33.75%) mainly megaloblastic anemia, haematological malignancy, aplastic anemia idiopathic thrombocytopenic purpura, hypoplastic anemia, thalassemia and iron deficiency anemia and liver pathologies (12.50%) mainly chronic liver disease, hepatocellular carcinoma, extrahepatic portal vein obstruction. Conclusion: Dengue fever as the most common cause of thrombocytopenia. Other common etiologies were megaloblastic anemia and other haematological diseases followed by chronic liver disease. Bleeding tendencies can be seen in many patients with severe thrombocytopenia thus, prompt diagnosis and immediate treatment of the underlying etiology is necessary.

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Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{177804,
        author = {Dr Namita Anand Soni and Dr Virendra Bapusaheb Yadav},
        title = {A study of the clinicohaematological profile of the patients presenting with thrombocytopenia in tertiary care hospital.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {12},
        pages = {3016-3022},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=177804},
        abstract = {Background: Thrombocytopenia is a common finding in patients admitted in tertiary care centre and its etiology is diverse.
Aim: To study the clinicohaematological profile of the patients presenting with thrombocytopenia in tertiary care hospital.
Materials and Methods: This study was a prospective study conducted over the period of two years conducted at MGM Medical College Aurangabad.With the relevant clinical and investigatory findings all patients with a platelet count of less than 1,50,000 were included in the study.
Result: The study included 80 patients, with the majority being males (62.50%) and a significant proportion aged between 18-30 years (40.00%).Platelet count analysis showed that 45.00% of the patients had counts below 50,000 per cubic millimeter, indicating severe thrombocytopenia.Etiological analysis revealed that febrile illnesses, particularly dengue fever (53.75%), were the most common cause of thrombocytopenia, followed by haematological disorders (33.75%) mainly megaloblastic anemia, haematological malignancy, aplastic anemia idiopathic thrombocytopenic purpura, hypoplastic anemia, thalassemia and iron deficiency anemia and liver pathologies (12.50%) mainly chronic liver disease, hepatocellular carcinoma, extrahepatic portal vein obstruction.
Conclusion: Dengue fever as the most common cause of thrombocytopenia. Other common etiologies were megaloblastic anemia and other haematological diseases followed by chronic liver disease. Bleeding tendencies can be seen in many patients with severe thrombocytopenia thus, prompt diagnosis and immediate treatment of the underlying etiology is necessary.},
        keywords = {Thrombocytopenia, clinicohaematoligical, etiology.},
        month = {May},
        }

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