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@article{177992,
        author = {Dr. S Rajalaxmi and Raveena S and Rohini S and Ronal Niward J and Sahana R},
        title = {NON-INVASIVE BIOIMPEDANCE BASED STOMACH ULCER DETECTION},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {12},
        pages = {2534-2539},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=177992},
        abstract = {Stomach ulcers, frequently caused by Helicobacter pylori (H. pylori) infection or prolonged use of non steroidal anti-inflammatory drugs (NSAIDs), remain a widespread gastrointestinal disorder with serious health consequences. While current diagnostic methods such as endoscopy and biopsy are effective, their invasive nature, high cost, and limited accessibility make them less suitable for widespread or early screening. This has created a demand for non-invasive, accurate, and affordable diagnostic alternatives. One promising molecular approach involves detecting H. pylori DNA in saliva using polymerase chain reaction (PCR), offering a simpler and less invasive diagnostic route. However, the efficiency of this method can be affected by variables in saliva composition—particularly pH—which may interfere with DNA stability and amplification. This study investigates how salivary pH variations influence PCR-based detection to improve its reliability. In parallel, the research explores bioimpedance analysis and localized temperature measurement as complementary non-invasive tools for ulcer detection. Bioimpedance evaluates the body’s electrical response to low-level alternating current, reflecting tissue integrity and physiological changes. Ulcerated gastric tissue typically exhibits altered electrical properties. Additionally, surface temperature changes—often due to inflammation—offer further diagnostic insight. This study proposes an integrated diagnostic framework combining molecular detection with bioimpedance and thermal profiling to improve the early identification of gastric ulcers. Initial findings indicate that this dual-modality approach enhances both sensitivity and specificity, especially for early-stage or asymptomatic cases. The ultimate objective is to develop a compact, cost-effective diagnostic device for use in both clinical and remote healthcare settings, advancing the future of non-invasive ulcer detection.},
        keywords = {Stomach ulcers, Helicobacter pylori Detection, Non-invasive, Bioimpedance Analysis, Surface Temperature Analysis, Dual-parameter.},
        month = {May},
        }