The Gut-Brain Axis: Scientific Evidence Supporting the Link Between Gut Health and Brain Function

  • Unique Paper ID: 179595
  • PageNo: 7020-7025
  • Abstract:
  • The gut-brain axis is a bidirectional communication network linking the gastrointestinal tract and the central nervous system, influencing cognition, mood, and neurological health. This article reviews the scientific basis for the adage “What’s good for your gut is good for your brain,” exploring mechanisms such as neurotransmitter production, immune modulation, and short-chain fatty acid (SCFA) metabolism. Empirical evidence suggests that diets rich in fiber, probiotics, and fermented foods enhance gut microbiota, potentially improving cognitive function and reducing psychiatric symptoms. However, individual variability and study limitations highlight the need for further research. This review synthesizes current evidence, evaluates dietary interventions, and proposes future directions for clinical applications, supported by recent advances in microbiota research.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{179595,
        author = {Laxman Harichandra Kamdi and Rajesh Narayan Bharsat and Gaurav Ulusha Bahiram and Sapana Dipak Vale and Yashoda R. Suryawanshi},
        title = {The Gut-Brain Axis: Scientific Evidence Supporting the Link Between Gut Health and Brain Function},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {11},
        number = {12},
        pages = {7020-7025},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=179595},
        abstract = {The gut-brain axis is a bidirectional 
communication network linking the gastrointestinal 
tract and the central nervous system, influencing 
cognition, mood, and neurological health. This article 
reviews the scientific basis for the adage “What’s good 
for your gut is good for your brain,” exploring 
mechanisms such as neurotransmitter production, 
immune modulation, and short-chain fatty acid (SCFA) 
metabolism. Empirical evidence suggests that diets rich 
in fiber, probiotics, and fermented foods enhance gut 
microbiota, potentially improving cognitive function 
and reducing psychiatric symptoms. However, 
individual variability and study limitations highlight 
the need for further research. This review synthesizes 
current evidence, evaluates dietary interventions, and 
proposes future directions for clinical applications, 
supported by recent advances in microbiota research.},
        keywords = {Gut-brain axis, microbiota, cognition,  mental health, probiotics, diet, neurodegenerative  diseases},
        month = {May},
        }

Cite This Article

Kamdi, L. H., & Bharsat, R. N., & Bahiram, G. U., & Vale, S. D., & Suryawanshi, Y. R. (2025). The Gut-Brain Axis: Scientific Evidence Supporting the Link Between Gut Health and Brain Function. International Journal of Innovative Research in Technology (IJIRT), 11(12), 7020–7025.

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