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@article{179927, author = {Bhumesh Parmanand Lilhare and Vidhan Pramod Jambhulkar and Akshay Ashok Naik}, title = {Formulation of Herbal Antifungal Ointment A Review}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {11}, number = {12}, pages = {9138-9144}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=179927}, abstract = {Fungal infections, also known as mycoses, range from superficial skin issues to severe systemic diseases. Due to the rising resistance to synthetic antifungal agents and their potential side effects, herbal alternatives have gained increased interest. This study aims to formulate and evaluate a herbal antifungal ointment using Melia azedarach (China Berry) and Hygrophila auriculata (Marsh Barbel), both of which are known for their traditional medicinal properties. The selected plants were collected locally, authenticated botanically, and subjected to methanol and ethanol extraction. The phytochemical constituents of the plants—such as limonoids, flavonoids, alkaloids, and triterpenes—contribute to their antifungal efficacy. The extracts were evaluated for their minimum inhibitory concentration (MIC) against Aspergillus niger, a common causative agent of fungal infections. Following extraction and MIC evaluation, the herbal ointment was formulated using standard excipients including stearic acid, glycerin, paraffin, and preservatives. The final formulation was tested for its antifungal activity and stability. The results demonstrated promising antifungal potential with minimal risk of side effects, supporting the efficacy of herbal combinations as a cost-effective and safe alternative for treating fungal skin infections.}, keywords = {Herbal antifungal ointment, Melia azedarach, Hygrophila auriculata, Minimum Inhibitory Concentration (MIC), Aspergillus Niger.}, month = {June}, }
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