Preliminary pharmacognostical and phytochemical analysis of CALOTROPIS GIGANTEA

  • Unique Paper ID: 179997
  • Volume: 12
  • Issue: 1
  • PageNo: 1952-1961
  • Abstract:
  • Calotropis gigantea, commonly known as the Crown Flower or Giant Milkweed, holds an important place in traditional medicine. This plant from the Apocynaceae family has been extensively used in Ayurveda, Unani, and folk healing systems to treat ailments such as fever, asthma, digestive disorders, skin diseases, and rheumatism. Various parts of the plantincluding its leaves, flowers, root bark, and latexare recognized for their medicinal properties. The latex is traditionally applied to skin infections, wounds, and tumors, while the root and bark are valued for their analgesic, anti-inflammatory, and antipyretic effects. Phytochemical investigations have identified a diverse array of bioactive compounds in C. gigantea, including cardenolides, flavonoids, triterpenoids, alkaloids, and glycosides, which are associated with its pharmacological activities such as antimicrobial, antioxidant, anticancer, antidiabetic, and anti inflammatory effects. componentsparticularly However, the latex certain and cardenolidesexhibit toxic properties, necessitating careful preparation and dosage regulation. Continued research is essential to isolate active constituents, elucidate their mechanisms of action, and validate their safety and efficacy through clinical studies. This review presents a comprehensive overview of the traditional uses, phytochemistry, and pharmacological potential of Calotropis gigantea, while highlighting key directions for future scientific investigation.

Copyright & License

Copyright © 2025 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{179997,
        author = {Manish yadav and Abhishek yadav and Alok yadav and Km Sarita},
        title = {Preliminary pharmacognostical and phytochemical analysis of CALOTROPIS GIGANTEA},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {1},
        pages = {1952-1961},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=179997},
        abstract = {Calotropis gigantea, commonly known as the 
Crown Flower or Giant Milkweed, holds an important 
place in traditional medicine. This plant from the 
Apocynaceae family has been extensively used in 
Ayurveda, Unani, and folk healing systems to treat 
ailments such as fever, asthma, digestive disorders, skin 
diseases, and rheumatism. Various parts of the 
plantincluding its leaves, flowers, root bark, and 
latexare recognized for their medicinal properties. The 
latex is traditionally applied to skin infections, wounds, 
and tumors, while the root and bark are valued for their 
analgesic, anti-inflammatory, and antipyretic effects. 
Phytochemical investigations have identified a diverse 
array of bioactive compounds in C. gigantea, including 
cardenolides, flavonoids, triterpenoids, alkaloids, and 
glycosides, 
which 
are 
associated 
with 
its 
pharmacological activities such as antimicrobial, 
antioxidant, anticancer, antidiabetic, and anti
inflammatory 
effects. 
componentsparticularly 
However, 
the 
latex 
certain 
and 
cardenolidesexhibit toxic properties, necessitating 
careful preparation and dosage regulation. Continued 
research is essential to isolate active constituents, 
elucidate their mechanisms of action, and validate their 
safety and efficacy through clinical studies. 
This review presents a comprehensive overview of the 
traditional uses, phytochemistry, and pharmacological 
potential of Calotropis gigantea, while highlighting key 
directions for future scientific investigation.},
        keywords = {Calotropis gigantea, Giant Milkweed,  Traditional Medicine, Phytochemistry},
        month = {June},
        }

Cite This Article

  • ISSN: 2349-6002
  • Volume: 12
  • Issue: 1
  • PageNo: 1952-1961

Preliminary pharmacognostical and phytochemical analysis of CALOTROPIS GIGANTEA

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