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@article{180421, author = {Garima Chand and Mohammad Younus}, title = {Role of MRI Diffusion Tensor Imaging (DTI) in Post Traumatic Spinal Cord Injury}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {12}, number = {1}, pages = {1781-1785}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=180421}, abstract = {Traumatic injuries of the spine are potentially catastrophic. If associated with neurologic damage, DTI is an advanced neuroimaging technique that is considered sensitive to cord changes not seen on conventional MR imaging. The aim of this study is to investigate the changes in spinal cord (DTI) parameters in patients with posttraumatic spinal cord injury. The study was performed in Radiodiagnosis Department Mahant Indresh hospital Dehradun in the period of January 2024 to January 2025, 25 patients presented with spinal cord transection after trauma (group 1) and 15 age matched controls (group 2) were included in this study. Conventional MRI and Diffusion tensor imaging (DTI) were performed in both groups. Time of imaging of group 1 varied between 1 to 3 years after trauma. Fraction anisotropy (FA) value was calculated at multiple levels proximal to the level of injury. This study demonstrates that FA values for patients with spinal cord injury are significantly lower than values in healthy individuals. Regional measurements of FA values at 5 cord levels showed significant decrease at the level of cord injury. DTI can be considered sensitive marker of cord injury if compared with conventional MR imaging. It can predict the need for early therapeutic intervention and can be considered as baseline pre-operative study and in follow up post stem cell therapy.}, keywords = {Diffusion tensor imaging, Spinal cord injury, Fractional anisotropy.}, month = {June}, }
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