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@article{181087,
        author = {Anitha C and Kinnari Divakar},
        title = {OPTIMISING METABOLIC HEALTH: EXPLORING THE SYNERGY BETWEEN MICRONUTRIENT AND COMPREHENSIVE LIFESTYLE INTERVENTIONS},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {1},
        pages = {3365-3374},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=181087},
        abstract = {Background: The global prevalence of metabolic 
syndrome (MetS) has reached epidemic proportions, 
and its impact on the Indian population cannot be 
underestimated. Currently, one in every four adult 
Indians has MetS. The current treatment strategy for 
MetS is mostly focused on medication and basic 
lifestyle changes; micronutrients are often overlooked. 
Objectives: The objective of the research was to use a 
synergistic approach of micronutrient optimization 
and lifestyle treatments to enhance specific metabolic 
markers (HbA1c and one or more of the waist-hip 
ratio, blood pressure, HDL, and triglyceride levels) in 
an urban Indian subject group with MetS. 
Material and Methods: A multidisciplinary healthcare 
team implemented a comprehensive treatment 
approach over a 3-month period for 20 individuals 
with MetS. The study included 20 patients with MetS 
seeking consultation at the Ultra Wellness Center- 
Truelife Functional Medicine Pvt. Ltd.  Given the 
observational nature of the study, a quantitative 
technique was applied for analysis. Descriptive 
statistics were used to test the difference in the chosen 
biomarker parameters before and after the 
intervention. 
Results: 
The intervention showed significant 
improvements in tested health parameters in both 
women and men. Mean HbA1c decreased from 6.9% 
(±1.462) to 6.0% (±0.823). Waist-to-hip ratio mean 
reduced for both women 0.79 (±0.074) to 0.75 (±0.059) 
and men 0.90 (±0.102) to 0.86 (±0.087). Blood pressure 
improved with mean systolic/diastolic readings 
dropping from 134 (±8.300) /86 (±4.807) mmHg to 126 
(±5.887) /82 (±2.865) mmHg. HDL cholesterol 
increased in women 38.5 (±4.009) to 48.5 (±7.774) 
mg/dL and men 45.8 (±8.715) to 53.8 (±10.306) mg/dL. 
Mean triglyceride levels decreased from 194 
(±144.211) mg/dL to 157 (±77.667) mg/dL. Participants 
reported a substantial increase in energy levels, with 
mean scores rising from 3.95 (±1.276) to 7.35 (±0.875) 
on a 10-point scale. 
Conclusion: The intervention yielded a positive 
outcome, indicating the importance of addressing 
micronutrient deficiencies in conjunction with lifestyle 
changes to enhance metabolic health in MetS patients. 
However, long-term effects must be assessed by 
further research with demographically diverse groups.},
        keywords = {Metabolic  Syndrome,  Metabolic  Parameters, Micronutrients, Lifestyle Interventions,  Urban Indian Population},
        month = {June},
        }