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@article{182163,
        author = {SURYAWANSHI SANDEEP B. and Bindu A. U. and Kale Abhijeet B. and Karke Kapil B.},
        title = {Anti-Urolithiatic Activity of An Aqueous Extract of Leucas Aspera Leaves In Ethylene Glycol (Eg)-Induced Urolithiasis Activity},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {2},
        pages = {1231-1243},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=182163},
        abstract = {Kidney stones, a major urology problem, are formed due to decreased urine volume or increased excretion of stone-forming components. Men are more likely to develop stones due to increased testosterone and estrogen levels, tissue breakdown, and metabolic waste. Pharmacological therapy for urolithiasis utilizing medicinal plants has been increasingly used to prevent recurrence. The evaluation of an aqueous extract of Leucas Aspera leaves in ethylene glycol induced (EG) urolithiasis activity on Albino Rat. Group I-Control were as received 5 % CMC (10ml/kg), Group II- received Ethylene glycol (1ml/kg), Group III- Received Ethylene glycol (0.75%) and cystone (Std) 750 mg/kg, Group IV- Received Ethylene glycol(075%) + AELA 250 mg/kg and Group V- Received Ethylene glycol(0.75%) + AELA 500mg/kg. Urolithiasis was induced by supplying drinking water mixed with 2% Ammonium chloride and 0.75% Ethylene glycol for 10 days. On 11th day three rats from each Group were kept in one metabolic cage and urine (pooled) collected for 24h was subjected for estimation of biochemical parameters like Urine volume, Urine PH, Creatinine, Calcium, Magnesium, Oxalate, Phosphate, Serum Constituents (Urea, Creatinine & Blood Urea Nitrogen). The result was showed that the ethanolic extracts of the plant produced significant anti-urolithiatic activity like that of standard.},
        keywords = {Ethylene glycol, Cystone, Leucas Aspera, Calcium oxalate.},
        month = {July},
        }