Design and Biological Assessment of a Novel Thiadiazol-Imidazole Based bimetallic complex with Antimicrobial and Anti-Inflammatory Potential

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Pooja Vilas Shinde; Dr. Willy Shah; Dr. Suhas Janwadkar

Design and Biological Assessment of a Novel Thiadiazol-Imidazole Based bimetallic complex with Antimicrobial and Anti-Inflammatory Potential

Authors: Pooja Vilas Shinde, Dr. Willy Shah, Dr. Suhas Janwadkar

Unique Paper ID: 182234
Volume: 12
Issue: 2
PageNo: 1292-1303

Keywords: Bimetallic complex Thiadiazole derivative Methyl imidazole Coordination chemistry antimicrobial activity Anti-inflammatory agent

Abstract:
A bimetallic complex was synthesized using a novel reagent, compound-A, derived from azole compound methyl imidazole and [N{3-(5-amino-2-thione-1,3,4-thiadiazole)}]. The synthetic pathway involved a condensation reaction between [N{3-(5-amino-2-thione-1,3,4-thiadiazole)}-methyl imidazole] and a substituted triazine carboxamide derivative, resulting in the formation of compound-A. This novel reagent was then used to form a bimetallic complex through coordination with copper metal under appropriate stoichiometric conditions. The structures of both Compound-A and its bimetallic complex were characterized using UV, IR, EDS, SEM, and NMR techniques. Preliminary biological evaluations revealed that the compound exhibits significant antimicrobial (both antibacterial and antifungal) as well as anti-inflammatory activities.

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Cite This Article

ISSN: 2349-6002
Volume: 12
Issue: 2
PageNo: 1292-1303

Design and Biological Assessment of a Novel Thiadiazol-Imidazole Based bimetallic complex with Antimicrobial and Anti-Inflammatory Potential

Available:https://ijirt.org/article?manuscript=182234

22 Jul, 2025

Design, Synthesis, and Antimicrobial Evaluation of a Novel Imidazole–Thiadiazole–Pyrazole Hybrid Nicotinamide Bearing a Trifluoroalkyl Ether Moiety.

Impact Factor
8.01 (Year 2024)

UGC Approved
Journal no 47859

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