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@article{183316,
        author = {Dr. Balasaheb P. Pagar and Mayur B. Kute and Dr. Yogeshwar R. Baste and Jagdish N. Ghotekar},
        title = {Eco-Friendly Fabrication of ZnO nanoparticles from Cyperus rotundus leaf extract for Photocatalytic Degradation, Antimicrobial Action, Pharmacokinetic study, Molecular docking and DFT insights.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {3},
        pages = {1075-1082},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=183316},
        abstract = {In the present study, zinc oxide (ZnO) nanoparticles were synthesized via a green and eco-friendly approach using Cyperus rotundus extract as a natural reducing and stabilizing agent. The synthesized nanoparticles were thoroughly characterized using UV-Visible spectroscopy, FTIR, XRD, SEM-EDS, BET-surface area, and LS techniques, confirming their crystalline nature and nanoscale morphology. The photocatalytic activity of the ZnO nanoparticles was evaluated by the degradation of malachite under solar visible light, demonstrating significant catalytic efficiency. Additionally, the nanoparticles exhibited potent antimicrobial activity against selected Gram-positive and Gram-negative bacterial strains, highlighting their potential as broad-spectrum antibacterial agents. Pharmacokinetic predictions, performed through in silico modeling, suggested favorable absorption, distribution, metabolism, and excretion (ADME) profiles, indicating their suitability for biomedical applications. Furthermore, density functional theory (DFT) studies provided insight into the electronic structure and reactivity of the ZnO nanoparticles, supporting their experimental performance with do it. The molecular docking of green synthesized nano ZnO with selected protein of E. coli was successfully achieved with docking score -1.7 Kcal/mol. The rainbow image, Li plot, Dim plot gives information regarding binding complex between E. Coli protein as a receptor and ZnO as a ligand This integrated study reveals that Cyperus rotundus-mediated ZnO nanoparticles possess multifunctional properties suitable for environmental and biomedical applications.},
        keywords = {ZnO nano, ADMET, Malachite green, molecular docking, Rainbow, Li plot, Dim plot, DFT.},
        month = {August},
        }