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@article{183911, author = {Dr.Mohankumar L and Shivashankar Govindan and Simonti Basak Sithi and Atem Edward Machok Atem}, title = {COVID-19 and Human Health: Exploring the Complex Interplay of Infection, Intervention, and Immunization}, journal = {International Journal of Innovative Research in Technology}, year = {2025}, volume = {12}, number = {3}, pages = {3465-3473}, issn = {2349-6002}, url = {https://ijirt.org/article?manuscript=183911}, abstract = {The COVID-19 pandemic has exerted a profound influence on global health, affecting individuals physically, mentally, and socially. This review aims to synthesize current evidence on the multifaceted health impacts of COVID-19, including both the direct consequences of SARS-CoV-2 infection and the indirect effects of public health interventions such as lockdowns. Longitudinal studies have reported significant declines in physical health, exacerbation of chronic conditions, and a rise in mental health issues, notably anxiety and depression, during the early phases of the pandemic. Concurrently, several positive public health outcomes were observed, such as improved hygiene behaviors, reduced rates of respiratory infections, and increased use of telemedicine and digital health technologies. A major focus of the pandemic response has been the development and global deployment of COVID-19 vaccines. While generally safe and effective, vaccines have been associated with rare adverse events. This review highlights the occurrence of cardiovascular complications, hematologic abnormalities including various forms of anemia, and autoimmune conditions like alopecia areata in certain individuals following vaccination. Specific populations, such as pregnant women and individuals with nutritional deficiencies or autoimmune predispositions, may require careful monitoring and follow-up. This review underscores the dual nature of the pandemic—as both a public health threat and a driver of systemic healthcare transformation. It calls for a balanced approach that maximizes the benefits of vaccination and pandemic control while ensuring continued research, patient-centered care, and long-term health system resilience.}, keywords = {}, month = {August}, }
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