The Development, And Synthesis of Some Derivatives of Triazole Schiff's Base as Feasible Antitubercular Drugs

  • Unique Paper ID: 184234
  • PageNo: 1337-1342
  • Abstract:
  • Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), continues to be a major cause of death worldwide, especially in developing nations. To increase patient compliance and reduce treatment durations, new anti-TB medications that are efficient, reasonably priced, compatible with HIV treatment, and active against drug-resistant strains are desperately needed. The design and synthesis of TLM analogues as possible anti-TB medicines was the main goal of this investigation. Twelve triazole analogues were created in order to overcome the difficulties in creating chiral TLM analogues. These compounds were thoroughly described using a variety of spectroscopic methods.

Copyright & License

Copyright © 2026 Authors retain the copyright of this article. This article is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

BibTeX

@article{184234,
        author = {Sagar Dhruvil Umeshbhai and Seema Kher},
        title = {The Development, And Synthesis of Some Derivatives of Triazole Schiff's Base as Feasible Antitubercular Drugs},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {4},
        pages = {1337-1342},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=184234},
        abstract = {Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), continues to be a major cause of death worldwide, especially in developing nations. To increase patient compliance and reduce treatment durations, new anti-TB medications that are efficient, reasonably priced, compatible with HIV treatment, and active against drug-resistant strains are desperately needed. The design and synthesis of TLM analogues as possible anti-TB medicines was the main goal of this investigation. Twelve triazole analogues were created in order to overcome the difficulties in creating chiral TLM analogues. These compounds were thoroughly described using a variety of spectroscopic methods.},
        keywords = {Mycobacterium tuberculosis, Thiolactomycin analogues, Anti-TB drugs, Triazole analogues, HIV-compatible treatment, Spectroscopic characterization, Chiral synthesis.},
        month = {September},
        }

Cite This Article

Umeshbhai, S. D., & Kher, S. (2025). The Development, And Synthesis of Some Derivatives of Triazole Schiff's Base as Feasible Antitubercular Drugs. International Journal of Innovative Research in Technology (IJIRT), 12(4), 1337–1342.

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