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@article{184854,
        author = {Salla pujitha and M. Parsharamulu and M.Venkataramana and Akula Ganesh and Y.Soundarya},
        title = {SIMULTANEOUS ESTIMATION OF AMLODIPINE AND VALSARTAN INPURE AND PHARMACEUTICAL DOSAGE FORM BY USING RP-HPLC METHOD},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {4},
        pages = {4596-4604},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=184854},
        abstract = {A simple, precise, and accurate reverse-phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the simultaneous estimation of Amlodipine and Valsartan in bulk drug and pharmaceutical dosage forms. Chromatographic separation was achieved on a Symmetry C18 column (4.6 × 150 mm, 5 µm) using a mobile phase consisting of Methanol and Triethylamine (TEA) buffer (pH 4.2) in the ratio of 40:60 v/v. The flow rate was maintained at 1 ml/min, with a column temperature of 40ºC. Detection was carried out at 260 nm using a Waters HPLC system equipped with an autosampler and PDA Detector (996 model). The injection volume was 10 µl, and the total run time was 6 minutes. The method exhibited good linearity, accuracy, precision, and specificity as per ICH guidelines. It was successfully applied for the quantitative analysis of Amlodipine and Valsartan in tablet formulations, demonstrating its suitability for routine quality control applications.},
        keywords = {Amlodipine, RP-HPLC, simultaneous estimation, Symmetry C18 column, Validation, Valsartan.},
        month = {October},
        }