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@article{185709,
        author = {Dr. Rashmi Prabha and Dr. Sneha Mohanty and Dr. Pratyush Ranjan Biswal},
        title = {Longitudinal Outcomes in Charcot-Marie-Tooth Disease: A Case Study Examination of Progressive Symptoms and Interventions.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {5},
        pages = {2544-2554},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=185709},
        abstract = {Background: Charcot-Marie-Tooth disease (CMT) encompasses a collection of genetic disorders that impact the nerves linking the brain and spinal cord to other parts of the body. CMT is the most prevalent inherited neuropathy. CMT impacts the sensory and motor nerves in the arms, hands, legs, and feet. Sensory nerves transmit information to the brain regarding sensations such as touch, temperature, pain, or pressure. Motor nerves are responsible for regulating muscle movements. When motor nerves deteriorate, they become incapable of sending signals to the muscles. The case study emphasizes how crippling and progressive ALS is to control symptoms and enhance quality of life, extensive therapeutic procedures such as strengthening, stretching, and functional training were used. The aim was to investigate the effectiveness of custom-made orthopaedic shoes (derby shoes) in conjunction with physiotherapy (twice a week) on a person with Charcot-Marie-Tooth disease over a period of 10 years. Case description and methods: A 27-year-old male with Charcot-Marie-Tooth disease since May 2024, complaining of pain, difficulty in walking, and shivering of legs after 1km. Physical examination, including ankle, knee, and hip muscle strength; sensory evaluation of foot and joint range of motion; self-reported assessment of pain, muscle atrophy noted in bilateral lower extremities.  Findings and outcomes: At the end of the program, lots of improvements are observed. Currently, he can maintain a good spinal curvature while sitting. As the strength of the bilateral lower extremities and hip girdle muscles was weak, he underwent the AAROM exercises for the bilateral lower extremities.  Conclusion:  Patients with Charcot-Marie-Tooth illness must be managed in physical medicine and rehabilitated as soon as possible following a clinical evaluation of their joint, muscular, and sensory health to create a program tailored to each individual.},
        keywords = {Obesity, RPE, Aerobic capacity, long interval HIIT, Medium interval HIIT.},
        month = {October},
        }