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@article{186655,
author = {NANDHAKUMAR N},
title = {COMPARATIVE QUALITY CONTROL TEST FOR TWO BRAND OF DICLOFENAC SODIUM &PARACETAMOL TABLET},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {6},
pages = {2682-2694},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=186655},
abstract = {Quality control is a critical aspect of the pharmaceutical industry, ensuring the identity, purity, safety, and efficacy of drug products. In this study, two types of combined diclofenac sodium and paracetamol tablets from different pharmaceutical companies were subjected to various quality control tests to determine their compliance with the standards specified in the Indian Pharmacopoeia. The evaluated parameters included weight variation, content uniformity, thickness, hardness, friability, disintegration time, dissolution rate, and pharmacopeial assay. The results indicated that all brands successfully met most of the pharmacopeial specifications. Both brands complied with the acceptable limits for weight variation and friability tests. However, variations were observed in hardness, disintegration time, and dissolution profiles among the tested samples. These differences may influence the therapeutic performance of the formulations. The study emphasizes that an ideal tablet should possess adequate hardness to maintain its mechanical integrity while ensuring optimal disintegration and dissolution for effective drug release and therapeutic action.},
keywords = {},
month = {November},
}
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