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@article{186900,
        author = {K Niharika and Dr. P V Madhavi Latha and K Suvarna and Dr. P Uma Devi},
        title = {Method Development and Validation of Simultaneous Estimation of Buprenorphine and Naloxone in Bulk and Pharmaceutical Dosage Forms by RP-HPLC Method},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {2734-2738},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=186900},
        abstract = {A rapid, sensitive, and precise reverse-phase high-performance liquid chromatography (RP-HPLC) method was developed for the simultaneous quantification of Buprenorphine and Naloxone using a Waters HPLC system. Chromatographic separation was achieved on an Inertsil ODS C18 column (250 × 4.6 mm, 5 µm particle size) maintained at ambient temperature. The mobile phase consisted of methanol and acetonitrile in the ratio of 85:15 (v/v), which was filtered through a 0.45 µm membrane filter prior to use. The flow rate was maintained at 1.0 mL/min, and detection was carried out at 247 nm using the PDA detector.},
        keywords = {Buprenorphine, and Naloxone, RP-HPLC.},
        month = {November},
        }