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@article{187223,
        author = {Shankar Bhagwan khokle and Shruti Sunil Wankhade and BHARATI NAMDEORAO RATHOD and Vaishnavi Raju Bawane and Trupti Amod Raut and Avinash S. jiddewar},
        title = {Study of SEDDS Used for Enhancement of Solubility and Oral Bioavailability},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {4875-4880},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187223},
        abstract = {The simplest and most practical way to administer deugs is orally. oral drug delivery systems are the most economical and dominate the global drug delivery industry. The main issue with oral medications poor aqueous solubility is the primary cause of formulations' low and inconsistent bioavailability. This could result in elevated therapeutic failure, lack of dose proportionality, and variability between and within subjects. According to estimates, 40% of active. water insoluble substances are poorly soluble in water. To increase the bioavailability of medications with one of the biggest problems with drug formulations is these characteristics. Different technological approaches are documented in the literature, such as solid dispersions, the formation of cyclodextrin complexes or micronation and various drug delivery system technologies. Incorporating these strategies, self-emulsifying drug delivery systems (SEDDS) have drawn increased interest for improving oral bioavailability while lowering dosage. Isotropic mixtures of oil, solvents, surfactants, and co-solvents/surfactants are known as SEDDS. The primary feature of these systems is their capacity to create micro-emulsions or fine oil -in-water (o/w) emulsions with mild stirring after dilution through the use of water. SEDDS may be an option for lipophilic medications, whose absorption is limited by their rate of dissolution promising method to increase oral absorption's rate and scope. This review article explains how self-emulsifying drug delivery systems can increase the solubility and bioavailability of poorly soluble drug.},
        keywords = {Self-emulsifying drug delivery system, Excipients, Types of SEDDS, Method of preparation, Application},
        month = {November},
        }