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@article{187488,
        author = {Saurabh Balu Betalse and Snehal Anil Bhosale and Jyoti Bhimraj Bhujade and Dr. Vandana Patil},
        title = {Integrating Herbal Medicine with Transdermal Technology: A Comprehensive Review},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {5266-5282},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187488},
        abstract = {A safe, non-invasive, and patient-friendly substitute for traditional administration methods is provided by herbal transdermal patches, an innovative drug-delivery technique. By avoiding hepatic first-pass metabolism and minimizing gastrointestinal adverse effects, these systems transport phytoconstituents straight through the epidermis into the systemic circulation. In order to maintain controlled, sustained release, a conventional herbal patch is made up of a polymeric matrix, drug reservoir, adhesives, permeability enhancers, and a protective backing layer. Lipid content, blood flow, moisture, pH, and the molecular properties of the herbal medication are among the physicochemical parameters that affect drug transport across the skin via transcellular, intercellular, or appendageal pathways. Although there are some drawbacks such skin irritation, inconsistent permeability, and expensive formulation costs, transdermal patches have many benefits like increased bioavailability, consistent plasma levels, convenience of administration, and extended shelf life. Pain relief, anxiety, sleeplessness, inflammation, asthma, and quitting smoking are among the uses. Quality and efficacy are guaranteed by thorough examination, which includes thickness, folding endurance, medication content, moisture analysis, in-vitro diffusion, and stability investigations. Herbal transdermal patches have great promise for future therapeutic innovation given the rising demand for natural medicines.},
        keywords = {Herbal transdermal patches; Components; Skin permeation; Application; and Future aspects.},
        month = {December},
        }