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@article{187733,
        author = {Dr. Kalidas Vijayan. and Dr. Avvinish Annant Narine and Dr. Vipin Kumar Tanwar},
        title = {Panchkarma Protocol in the Management of Kshina Shukra (Oligospermia): A Case Report.},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {6},
        pages = {6480-6488},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=187733},
        abstract = {Background: Oligospermia, defined by subnormal sperm concentration, is one of the most common causes of male-factor infertility. Biomedical literature identifies oxidative stress, endocrine dysregulation, genitourinary inflammation, metabolic syndrome, and environmental exposures as central contributors to reduced spermatogenesis. Ayurveda conceptualizes similar clinical patterns under Kshina Shukra and Shukravaha Srotodushti, conditions attributed primarily to Vata–Pitta aggravation, impaired tissue metabolism (Dhatvagni Mandya), and depletion of Shukra Dhatu. Panchkarma, particularly Basti therapy along with Rasayana formulations, is traditionally recommended to restore reproductive tissue homeostasis. Objective: To evaluate integrative Ayurvedic therapeutic mechanisms in the management of oligospermia and present a case report demonstrating restoration of seminal concentration following a structured Panchkarma protocol. Methods: A comprehensive literature review was conducted examining biomedical and Ayurvedic evidence on male infertility. A case report of a 36-year-old married male with eight years of primary infertility and laboratory-confirmed oligospermia is presented. Treatment included Haritakyadi Churna for Koshta Shuddhi, followed by a 14-day Panchkarma regimen of Saptaprasritika Niruha Basti and Tila Taila Anuvasana Basti and subsequent administration of Vrishya Ghrita. Semen analyses from 21/07/2025 and 25/09/2025 were evaluated as primary outcome measures.  Results: Sperm concentration increased from 14 to 60 million/mL following therapy, indicating substantial improvement in spermatogenesis. Motility and morphology showed modest positive shifts. No adverse events were noted. Conclusion: This case suggests that Panchkarma-based integrative therapy may enhance seminal concentration in oligospermia. Controlled trials are needed to validate clinical efficacy and elucidate mechanisms.},
        keywords = {Ayurveda, Basti, Oligospermia, Panchkarma, Rasayana, Vajikarana.},
        month = {November},
        }