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@article{187981,
author = {SAMREEN TABASSUM HUSSAIN and Dr.SUDHA PARIMALA},
title = {Role of diuretics in the management of hypertension},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {7},
pages = {300-302},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=187981},
abstract = {Global burden of hypertension: prevalence, morbidity, mortality, public health impact.Need for effective, affordable, long-term antihypertensive therapy.Historical evolution: introduction of diuretics in hypertension treatment (since 1950s).Rationale for the thesis: despite many newer antihypertensive classes, diuretics remain widely used — importance to understand their role, benefits, limitations, and optimal use.Differences by class: Thiazides act on distal convoluted tubule; loop diuretics on loop of Henle; potassium-sparing on collecting ducts/aldosterone-sensitive segments. Summarize the enduring vital role of diuretics in hypertension management.Highlight that despite newer antihypertensive drugs, diuretics remain essential because of proven efficacy, affordability, versatility, and long-term outcome data.Emphasize the importance of judicious use: correct class and dose selection, monitoring, and combination therapy when needed.Point to areas where further research or careful clinical judgment is needed (e.g., diuretics in metabolic syndrome; balancing benefits vs metabolic risks).},
keywords = {antihypertensive drugs,Thiazides , ducts/aldosterone-sensitive segments.},
month = {November},
}
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