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@article{186497,
author = {VADLA TEJASWI and Dr.R.SUTHAKARAN},
title = {FORMULATION AND EVALUATION OF IMMEDIATE RELEASE OF CENOBAMATE},
journal = {International Journal of Innovative Research in Technology},
year = {2025},
volume = {12},
number = {6},
pages = {2107-2126},
issn = {2349-6002},
url = {https://ijirt.org/article?manuscript=186497},
abstract = {The present study was aimed at the formulation and evaluation of immediate release tablets of Cenobamate, an antiepileptic drug, to achieve rapid onset of action and improved patient compliance. A total of nine formulations (F1–F9) were prepared by direct compression method using different concentrations of super disintegrants. All the prepared formulations were subjected to pre-compression and post-compression evaluation parameters, which were found to be within the acceptable limits as per the Indian Pharmacopoeia (IP) specifications. Among the formulations, F6 exhibited superior performance with rapid disintegration time, acceptable hardness, friability, and uniform drug content, along with enhanced in vitro drug release profile compared to other formulations. Thus, F6 was identified as the optimized formulation, demonstrating its potential for the development of an effective immediate release dosage form of Cenobamate.},
keywords = {Cenobamate, Immediate Release Tablets.},
month = {November},
}
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