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@article{188093,
        author = {Anshika Y. Bhati and Monali R. Kakde and Khushal B. Darunkar and Nilesh O. Chachda},
        title = {Transdermal drug delivery device based microneedle},
        journal = {International Journal of Innovative Research in Technology},
        year = {2025},
        volume = {12},
        number = {7},
        pages = {644-657},
        issn = {2349-6002},
        url = {https://ijirt.org/article?manuscript=188093},
        abstract = {Microneedle (MN) technology, a ground breaking advancement on site of topical drug delivery, offers a low impact, painless, and effective approach of administering medications, biomolecules, and vaccines. By creating micro scale channels across the stratum corneum, MNs enhance the entry of drugs that might not be sufficiently absorbed through conventional routes. MNs are divided into solid, coated, dissolving, hollow, and hydrogel-forming forms based on their composition and design; each type allows for exact control over drug release kinetics and therapeutic targeting. The use of biocompatible and biodegradable polymers, metals, ceramics, and carbohydrate-based materials to increase mechanical strength, safety, and transport efficiency has increased recently due to advancements in materials science. MNs have been widely used in a variety of sectors, including gene therapy, oncology, diabetes treatment, immunization, ophthalmology, dermatology, and cosmetics. New studies combine MNs with photo-thermal agents, biosensors, and nanoparticle carriers for controlled release and diagnostic applications. Optimizing large-scale manufacturing, mechanical stability, drug-loading capacity, and regulatory approval still present difficulties despite notable advancements. However, MN-based systems are still developing as viable next generation drug delivery platforms that are accurate, patient-friendly, and self-administered.},
        keywords = {Microneedles, Transdermal drug delivery system, Microchannels, Self-administration, Hollow Microneedle, Poke and Flow,},
        month = {December},
        }